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THE EFFECTS OF HIGH POROSITY STENT CONFIGURATIONS ON CEREBRAL ANEURYSM HEMODYNAMICS

机译:高孔隙率支架配置对脑动脉瘤血流动力学的影响

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Coil embolization is the most common endovascular treatment for cerebral aneurysms at many centers [1]. Nevertheless, the coiling of wide-neck aneurysms is a challenge. Incomplete filling of the aneurysmal sac due to coil configuration challenges and aneurysmal growth can often lead to recurrence. To assist treatment with coils, clinicians may deploy a high porosity stent in a staged process to act as a supporting bridge for coils. The stent is first deployed across the aneurysmal neck, and multiple coils are then deployed into the aneurysmal sac 6-8 weeks later [2]. Under certain circumstances, coil deployment is not possible and high porosity stents alone are used for treatment [2-3], When deploying stents at bifurcations, clinicians have several configuration options [4]. A previous quantitative in-vitro study conducted by our group found significant differences in fluid dynamic performance among stent configurations. In this work, we investigate the detailed fluid dynamics that lead to these differences.
机译:线圈栓塞是许多中心对脑动脉瘤的最常见的血管内治疗[1]。然而,宽颈动脉瘤的卷曲是一项挑战。由于线圈构造挑战和动脉瘤生长导致动脉瘤囊的不完全填充可能导致复发。为了用线圈进行辅助处理,临床医生可以在分级过程中展开高孔隙率支架,以充当线圈的支撑桥。首先将支架展开在动脉瘤颈部,然后将多个线圈展开到动脉瘤囊6-8周后[2]。在某些情况下,不可能的线圈展开,单独的高孔隙率支架用于治疗[2-3],当在分叉处部署支架时,临床医生有几种配置选项[4]。我们的群体进行的先前定量的体外研究发现支架配置中的流体动态性能的显着差异。在这项工作中,我们调查了导致这些差异的详细流体动力学。

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