Mesoporous Hybrid Silica Particles as Nanodevices for Cell-Specific Drug Delivery and Targeting Applications

摘要

Targeted drug delivery is one of the key aims in medical sciences today. By employing nanotechnology it may be possible to deliver, or even co-deliver, drugs in a cell- and tissue specific manner. Targeting is especially relevant in the context of cancer therapies, as most of the commonly used anticancer drugs have serious side-effects due to unspecific action on healthy cells. Moreover, drug delivery will play a vital role in realizing the potential success of newly identified therapeutic agents, a significant percentage of which are poorly soluble in water.