Diagnosis of unexplained cardiac arrest: role of genetic screening for channeloppathies

摘要

Cardiac arrest without evidence of rythm or structural heart disease may be due to genetic disorders with low penetrance. Our aim was to study the usefulness of genetic screening in a small sample of patients with idiopathic ventricular fibrillation. Nine patients with apparently unexplained cardiac arrest and no evident cardiac disease were included. They underwent systematic evaluation including genetic and pharmacological testing for the long QT and Brugada Syndrome.