Histological evaluation of pulp tissue and periodontal regeneration in autogenous tooth transplantation

摘要

Objective: The aim of this study was to evaluate the pulp tissues and periodontal regeneration, in autogenous tooth transplantation, with application of Emdogain in the socket. Methods: The study group comprised 3 Beagle dogs, in which 24 incisors and premolars were transplanted to the recipient sockets after mechanical preparation. The Emdogain group (E), the saline group (S) and the control group (C) contained 12, 12 and 6 teeth, respectively. Clinical examinations were performed every week and were sacrificed 9 weeks later. Subsequently, decalcified sections were prepared for routine histological immunohistochemical evaluation. Ordinal scores were analyzed using ,the t-student test (p = 0.05).Results: All the transplanted teeth survived. No statistically significant difference was found among the complete healing in all treatment groups (p = 0.303). The mean occurrence of inflammatory (p = 0.015) and replacement root resorption was high with saline solution, compared with Emdogain group, with and significant difference (p = 0.015 and p = 0.041, respectively). Conclusions: The Emdogain does not seem to enhance the regeneration of periodontal and pulp tissues, but decrease the inflammatory and the replacement root resorption.