A Highly Sensitive Interdigital Biosensor for Cancer Cells Dielectric Characterization Using Microwave Frequencies

摘要

This paper describes the design and assessment of a highly sensitive micro biosensor functioning at microwave frequencies. The proposed technique allows single step dielectric characterization and measurement of human cells. In this work, two resonators are etched on the center of the planar device. Their microscopic sensing area is an Inter-Digital Capacitor (IDC) used to guarantee an intense electric field, especially between 15 and 35 GHz. Hence, the inter resonators detection capabilities are demonstrated on normal (HaCaT) and cancerous (Glial) biological cells, which are shaped as solid octagonal with the electrical proprieties found in the literature. Experimental results on human cells are presented showing the biosensor's ability to differentiate at least two particular cell types by means of frequency.