Sub-Parts-Per-Million Mass Accuracy and mDa Visualization of FT-ICR Mass Spectrometry Imaging Data

摘要

1. Correction for total and relative ion abundance improves mass measurement accuracy for FT-ICR MS imaging to sub-ppm levels for endogenous lipids. 2. The "Mosaic Datacube" allows spectral visualization at a bin width of 0.001 Da across the entire mass range of interest. 3. Mass differences of 8 mDa are resolved in the Mosaic Datacube.