Determination of GDC-0068 and its metabolite in rat and monkey plasma using high-performance liquid chromatography coupled to mass spectrometry

机译：用高效液相色谱法耦合到质谱法测定大鼠和猴等离子体中GDC-0068及其代谢物

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These two assays were validated following the GLP guidelines and showed good accuracy, precision and selectivity. These assays were used to support the sample analysis of the non-clinical toxicity studies for IND filing.

机译：在GLP指南下验证了这两个测定，并显示出良好的准确性，精度和选择性。这些测定用于支持IND归档的非临床毒性研究的样本分析。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2012年||共1页
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Xiaorong Liang; Bianca M. Liederer; Brian J. Dean; Sarah Burke; Dale Campbell; John Perkins; Yuzhong Deng;
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Determination of GDC-0068 and its metabolite in rat and monkey plasma using high-performance liquid chromatography coupled to mass spectrometry

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