Comparison of Relative Quantitation Strategies Using Shot Gun Mass Spectrometry

摘要

Controlled Samples: 1. The observed ratios in 1:1 controlled samples showed that all tech niques performed with reasonable precision, being mTRAQ the one with more variation in the measurements. 2. Although dimethyl labelling proved to be the most accurate when mea suring high ratios, in general, for all chemical labelling techniques the ac curacy of the relative quantitation measurements decreased as the dy namic range increased,