Antibacterial Suture Reduces Surgical Site Infections in Coronary Artery Bypass Grafting

摘要

Surgical site infections (SSI) still remain a major complication in cardiac surgery. In this study, we evaluated the impact of Triclosan-coated polyglycatin 910 sutures on frequency of SSI during the early postoperative phase. A total of 100 patients scheduled for coronary artery bypass grafting (CABG) were prospectively randomized to receive either Triclosan-coated polyglycatin 910 suture (Group A, n=50) or traditional Triclosan-uncoated suture (Group B, n=50) for wound closure. Total number of SSI was developed in 6 of 50 patients (12%) in Group A, and in 16 of 50 patients (32%) in Group B (p=0.03 vs. Group A). Though the groups showed no significant difference in chest wound infection, there was significant difference in leg wound infection (Group A 10% and Group B 28%, p=0.04). The use of Triclosan-coated polyglycatin 910 sutures is associated with less SSI following CABG.