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Microneedles electrodes for living cells

机译:微针电极用于活细胞

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This paper shows the technology development of microneedles electrodes for living cell applications. The study includes the fabrication of cantilever electrodes to monitor individual cells. The technology is based on silicon micromachining by combining Deep Reactive Ion Etching and Focused Ion Beam (FIB) nanomachining. Cell biology applications require micrometer size electrodes, smaller than living cells (~20 ??m), and biocompatible materials. The metal electrode is fabricated in aluminum and passivated by silicon oxide. The opening of the tip electrode by FIB is also performed. Finally, the tip of the electrode is covered by a nanometer thick gold layer deposited by electroless to improved biocompatibility and electrochemical conductivity. The study also addresses questions concerning to the pre-treatment of the aluminum layer before gold deposition in other to improve the adherence and conductivity.
机译:本文介绍了微针电极的技术开发,用于活性细胞应用。该研究包括制造悬臂电极以监测单个细胞。该技术通过组合深反应离子蚀刻和聚焦离子束(FIB)纳米机来基于硅微加工。细胞生物学应用需要微米尺寸电极,小于活细胞(〜20?m)和生物相容性材料。金属电极在铝中制造并通过氧化硅钝化。还执行FIB的尖端电极的开口。最后,电极的尖端被沉积的纳米厚金层覆盖,以改善生物相容性和电化学电导率。该研究还解决了关于金沉积前铝层预处理的问题,以改善粘附和电导率。

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