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CONTROL OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) IN CLINICS THE COMMUNITY

机译:在诊所和社区中控制耐甲氧西林金黄色葡萄球菌(MRSA)

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Staphylococcus aureus is a Gram positive opportunistic pathogen that is part of the commensal micro flora in many species, including horses. As an opportunist, S. aureus can reside in or on a host without any apparent problems, however infections canoccur in certain situations. One problematic aspect of S. aureus is its tendency to develop or acquire resistance to antimicrobials. Penicillin-resistant S. aureus was identified shortly after widespread use of penicillin in humans; first in hospitals, then in the general population. This resistance was mediated through beta-lactamase production, so antimicrobials that were resistant to the effects of beta-lactamase (i.e. methicillin) were developed. However, methicillin-resistant S. aureus (MRSA) emerged in humans shortly thereafter.
机译:金黄色葡萄球菌是一种克阳性机会理性病原体,是许多物种的共数微菌群的一部分,包括马匹。作为机会主义者,S.金黄色葡萄球菌可以在没有任何明显问题的情况下居住在宿主中,但是在某些情况下感染Canoccur。金黄色葡萄球菌的一个有问题方面是它倾向于发展或获得对抗微生物的抵抗力。在人类中,青霉素广泛使用后不久鉴定了青霉素的金黄色葡萄球菌;首先在医院,然后在一般人群中。这种阻力通过β-内酰胺酶生产介导,因此开发了抗β-内酰胺酶(即甲氧西林)效应的抗微生物。然而,耐胰岛耐金黄色葡萄球菌(MRSA)在此后不久出现在人类中。

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