Dosimetry of P Radiocolloid for Radiotherapy of Brain Cyst

摘要

In the radionuclide treatment of some forms of brain tumors such as craniopharyngiomas, the selection of the appropriate radionuclide for therapy is a key element in treatment planning. The aim of present study was to study the influence of ~(32)P in the radionuclide therapy of craniopharyngioma cysts by considering to its dose rate to sites of the diseased tissues. Dosimetry calculations were performed by utilizing the MCNP4C radiation transport code. Analytical dosimetry was additionally performed using the Loevinger formula in MATLAB software for ~(32)P. Each result was compared under identical conditions. The needed activity for injection according to the cyst volume was also obtained in the case of ~(32)P. At the range of 200-300 Gy dose, changes of activity was studied too. Increasing desired dose for therapy results in growth of essential activity for treatment.