Multispectral Fluorescence Imaging for Tumor Detection and Molecular Biology

摘要

The use of a multispectral imaging system provides possibilities to map all information encoded in the spectral fingerprint of an exogenous or endogenous chromophore in biological media. The spectral information has been used to demarcate the spatial extent of superficial skin tumours. Monitoring the fluorescence emitted from the photosensitizer over time yield information about the photodynamic treatment progression. The multispectral approach will also enable depth estimation of a lesion and thus allow quantitative measurements of a fluorophore as shown by the results presented