MULTIPLEXED OPERATION OF HIGH RESOLUTION ORTHOGONAL MULTI-REFLECTING TIME-OFFLIGHT MASS SPECTROMETER

摘要

Multi-reflecting TOF MS incorporate extended ion flight paths to increase resolution, however this is at the expense of duty cycle. Upstream trapping to accumulate ions results in loss of mass accuracy. Alternatively, multiplexing of TOF spectra has been proposed by numerous researchers [1,2,3]. Here we describe the implementation of Encoded Frequent Pushing (EFP) [4, 5], where a repeated sequence of unique time interval pusher pulses is applied.