FIRST REPORT ABOUT THE STRUCTURE OF AN IMMUNOADJUVANT SAPONIN FRACTION FROM QUILLAJA BRASILIENSIS LEAVES BY LC-ESI-IT-MS~n

摘要

Quillaja brasiliensis is an endemic tree species in Brazil and Uruguay. It has been shown that the aqueous extract and some of the purified saponin fractions obtained from its leaves have immunoadjuvant activity comparable with Quil-A, the main commercial adjuvant product based on Q. saponaria saponins [1, 2]. The aim of this study was to perform a preliminary structural characterization of the immunoadjuvant fraction of saponins designated as Fraction B (FB).