Mapping of protein-protein interactions in 14-3-3zeta homodimer: Combination of photo cross-linking protein nanoprobe with mass spectrometry.

摘要

The novel methodological approach of photo-initiated cross-linking protein nanoprobe with mass spectrometry extends the number of residues within homodimer interface of 14-3-3zeta. These findings are in accordance with previously published data obtained by chemical cross-linking with EDC, H/D exchange mass spectrometry or X-ray crystallography (PDB 3DHR).