DESI TOF imaging at 30 scans/sec was achieved using the SYNAPT G2-Si and Xevo G2-XS. Despite a decrease in sensitivity, the image quality and MS resolution were not affected by the increase in acquisition speed. It was demonstrated that DESI imaging at up to 10 scans/sec was feasible with ion mobility separation. Fast transfer MS/MS IMS DESI imaging allowed the generation of ion images for isobaric species at a scan rate of 6 scans/sec Combining fast DESI imaging with "Real time" viewer software allowed the visualisation of 4 m/z on the fly to assess the quality of the experiment.
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机译:使用Synapt G2-Si和Xevo G2-XS实现30次扫描/秒的Desi TOF成像。尽管灵敏度降低,但图像质量和MS分辨率不受采集速度的增加影响。结果证明,最多10个扫描/秒的Desi成像与离子迁移率分离是可行的。快速传输MS / MS IMS DESI成像允许以6扫描/秒的扫描速率产生异物型物种的离子图像,与“实时”观看者软件相结合的快速DESI成像,允许在飞行中可视化4 M / Z来评估实验的质量。
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