CHEMICAL PROFILING OF ACTAEA SPECIES AND COMMERCIAL PRODUCTS USING UPLC-QTOF-MS

摘要

The application of UPLC-QTOF-MS for multivariate analysis of black cohosh and its commercial products is a powerful approach for authenticating commercial products sold in the market. All the reference black cohosh and adulterant species were successfully classified against each other using their LC/MS chemical profiles. This result allowed the authentication of the 16 commercial black cohosh species. Only 11 of the 16 products were found to contain the North American (A.racemosa) specie while the other 5 contained either the substituted Chinese black cohosh species (C. foetida and A. dahurica) or the common adulterant species, S.chinensis or A.biternata. Progenesis QI provides a comprehensive workflow approach for chemical profiling of natural products from processing large LC/MS datasets to conducting multivariate analysis with marker identification.