Overcoming Challenges of Captisol Interference in Reversed-Phase based Analytical Characterization

机译：克服Captisol干扰在基于反相的分析特征中的挑战

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Mini-purification by IMAC spin column is implemented as sample pretreatment prior to RP-LC-MS intact mass analysis of Captisol containing formulation samples. Filter-assisted peptide mapping allows successful analysis of Captisol containing formulation samples.

机译：通过IMAC旋转柱的迷你纯化在RP-LC-MS完整的含有制剂样品的RP-LC-MS完整分析之前实现样品预处理。过滤辅助肽映射允许成功分析含有制剂样品的Captisol。

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《ASMS Conference on Mass Spectrometry and Allied Topics》|2016年|1CD|共1页
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Hai Yue; Teresa Barrier; Robert Hong; Izydor Apostol; Xin Zhang;
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中图分类 TB994.5-53;
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Overcoming Challenges of Captisol Interference in Reversed-Phase based Analytical Characterization

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