High resolution mass spectrometry detection and identification of pharmaceutical transformation products and metabolites in hospital effluents and wastewater

摘要

Anticancer drugs are found in relatively low concentrations in the aquatic environment Degradability of two cancer drugs was investigated: Etoposide in chlorine-free water where out of two transformation products one (BP1) was found in environmental samples while the parent ETP was not Methotrexate in batch biodegradation system is readily biodegradable and broken down to TPs, of which nine were successfully identified.