A Low-Flow/Liquid-Junction Capillary Electrophoresis/Mass Spectrometry Interface for Nonvolatile Additive

摘要

A liquid-junction/low-sheath-flow interface capable of using nonvolatile additive was developed. Under the appropriate pH value of the buffer, the ion suppression caused by nonvolatile additive anions could be reduced. Preliminary results reveal that this interface is able to employ nonvolatile additive such as phosphate salt or DS salt in CE-MS with good separation efficiency and without the suppression effect of nonvolatile anions.