A Novel Photo-cleavable Protein Interaction Reporter (pcPIR) Cross-linking Strategy to Study Protein-protein Interactions

摘要

The photo-cleavable characteristics of pcPIR was demonstrated. The feasibility of applying pcPIR strategy on cross-linking standard peptides were demonstrated. pcPIR can cross-link E. coli proteins in vivo. The strategy of coupling pcPIR with LC technique was demonstrated.