Thermoanalytical Characterization and Antimicrobial Activities of Mg(II) and Cu(II) Complexes with Bioactive Ligands

摘要

Preparation, complexometric titration, elemental (CHN), spectral (FTIR), thermogravimetry (TG) and differential thermal analysis (DTA) have been used to investigate the thermal behavior and structure of Mg(ac)_2(mpc)_3.3H_2O(I), Mg(Clac)_2(mpc)_2.3H_2O(II), Mg(Cl_2ac)_2(mpc)_2.3H_2O(III), Mg(Cl_3ac)_2(mpc)_2.3H_2O(IV) and [Cu(ac)_2(mpc)]_2.3H_2O(V) (ac = CH_3COO~-, Clac = ClCH_2COO, Cl_2ac = Cl_2CHCOO~-, Cl_3ac = Cl_3CCOO~- and mpc = methyl-3-pyridyl carbamate). Thermal decomposition of the Compounds is a multi-stage processes. The composition of the compounds and the solid state intermediate and resultant products of thermolysis had been identified by means of elemental analysis and complexometric titration. The possible scheme of thermal decomposition of the Compounds is suggested. Heating the compounds first resulted in a release of water molecules. The TG results show that the loss of the volatile ligand (mpc) occurs in one step for compounds II, IV and V and in two steps for Compounds I and III. The final solid product of thermal decomposition was MgO or CuO. The thermal stability of the compounds can be ordered in the sequence: I=II