Dendrimer crosslinked collagen hydrogels modified with YIGSR peptide and their effects on cellular behaviors of human corneal epithelial cell line and nerve regeneration

摘要

The results of the current study suggest that cell adhesive peptides can be incorporated into dendrimer crosslinked collagen gels by way of the dendrimers with only minor interference to crosslinking, producing transparent, mechanically strong and more biocompatible collagen gels. Human corneal epithelial cell adhesion, proliferation, stratification and nerve extension were promoted by YIGSR modification.