Triethylene glycol derived from composite resins modulates the expression of genes associated with biofilm formation and other virulence factors in Streptococcus mutans

摘要

The presence of TEG upregulates the expression of gtfB and may modulate virulence properties such as biofilm formation and acid tolerance. These are some of the first reports describing the interactions of composite resin-derived BBP's on the physiological functions of oral bacteria at product concentration levels found in vivo. The current work highlights the potential for in vivo consequences of BBP's with respect to biofilm formation and microbial survival.