Design and Fabrication of Biomorphic Tissue Engineering Scaffolds using Trigonometric Templates

摘要

Though the natural manifestations of minimal surface forms have been observed in biology2, and the computational framework to create such a geometry has been in place for decades, to the best of our knowledge, no attempt has been made so far to fabricate them using rapid prototyping devices let alone investigate their potential use as tissue surrogates. We have presented a trigonometric approach to physically realize and mechanically characterize these novel templates. This viable morphology, when replicated at macro (tissue) level may also have profound implications on cell migration and tissue growth and may provide an optimal biomorphic tissue analog.