Neonatal Group B Streptococcal Disease in Northern Part of Estonia

摘要

Before GBS prevention program was initiated in the Northern part of Estonia in 2000, no data existed on the incidence of neonatal GBS infection in the country. The aim of this study is to establish the incidence of neonatal GBS disease, as well as to assess its risk factors and clinical features. We retrospectively analyzed the neonatal cases of CjBS disease in different Northern Estonian hospitals over the period of 01/01/2000 to 31/12/2005. Fifty three cases were identified, of which 96% had early-onset disease. 84% of the 53 cases had perinatal risk factors. Laboratory findings showed that 49% had culture-verified GBS septicaemia/meningitis. The incidence of invasive neonatal GBS disease in Northern part of Estonia is 0.46 cases per 1000 live births.