A digital business ecosystem (DBE) is a closed or semi-closed system of small and medium enterprises (SMEs), which will come together in cyberspace in the same way that companies gather in a business park in the physical world. These companies will interact with each other through buyer-seller relationships. The purpose of this work is to develop a methodology that will allow one to study the ecosystem under various conditions and we present here a model for the mutual interactions between companies in a DBE and a methodology that can allow one to study the dynamics of a digital business ecosystem. Furthermore we present a quantitative model for studying the dynamics of such a system, inspired by human physiology and attempting to capture many aspects of the way companies interact with each other, including the quantitative modelling of trust and mistrust.
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