Reduction in Blood Product Usage in Routine Use of Mini Bypass Systems During Extracorporeal Circulation

摘要

A prospective, randomized study of 60 consecutive CABG patients comparing blood product usage and postoperative bleeding in 30 mini bypass systems (n=30) to 30 conventional systems (n=30) showed a statistically significant trend in reduced blood product usage. In the mini bypass group, no homologous blood transfusions were given in the OR, 27% of the patients received at least one unit of homolgous blood. In the control group 43% of the patients received at least one unit of blood in the OR or in the ICU, and there was a stastistically-significant 38% reduction in homologous blood product use (p=0,05). Patients receving homologous blood also showed a significant reduction in transfused volume (0,53 +- 0,90 units mini bypass vs 1,3 +- 1,93 units conventional, p<0,05) and in fresh frozen plasma (0 units vs 3 units FFP, p<0,001). A reduction in post op beeding was also seen (365,2 +- 495,7 ml mini bypass vs 825,5 +- 975,87 ml conventional, p<0,05). Mini bypass can thus reduce hemodilution and donor blood usage in routine CABG, and can reduce post-op bleeding.