ST elevation myocardial infarction (STEMI) in the right ventricle (RV) associated with right coronary artery (RCA) occlusion is known to have high hospital mortality. The hypothesis tested in this study is: right precordial leads V4R and V5R help detect STEMI in the right ventricle. ECGs from 1,970 subjects were collected in Ruijin Hospital (n = 1,342), Shanghai, China and Lund University Hospital, Lund (n = 565), Sweden. All ECGs were recorded with additional leads on the right precordial location in V4R and V5R. Our results show that the subjects with middle to upper RCA occlusion often show ST elevation in leads V4R and V5R and ST depression in lateral leads I, aVL, V5-V6, and are often undetected as STEMI or AMI in the standard 12-lead ECG. We conclude that adding V4R and V5R to standard ECG recording in assessing patients presenting with acute coronary syndrome is an easy and convenient way to increases the sensitivity of STEMI detection.
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