FLUX AND PROTEIN REJECTION IN CROSS-FLOW MICROFILTRATION OF YEAST/PROTEIN BINARY SUSPENSION

摘要

The mechanism of cross-flow microfiltration of yeast/protein binary suspensions is studied. The formation and the properties of the filter cake and the rejection of protein under various conditions, such as cross-flow velocity, filtration pressure, etc., are measured and discussed. Yeast and BSA (bovine serum albumin) are suspended in de-ionized water to prepare a binary suspension. The experimental results show that the filtration flux increases with increasing the cross-flow velocity and the filtration pressure. The BSA rejection is determined by the protein depositing probability on the cake surface and the cake properties. An increase in the cross-flow velocity or the filtration pressure causes the rejection of BSA to be higher. A theoretical model based on the filtration theory and the concentration polarization model is derived in this study. The pseudo-steady filtration flux and protein rejection for a given condition can be predicted using the proposed model.