Histologie and Ultrastructural Soft Tissue Changes Following Midface Distraction Osteogenesis

摘要

The present work investigated the effects of midface distraction on adjacent soft tissue elements, including the zygomaticus major muscle, infraorbital nerve, and facial artery, in our congenital caprine cleft palate model. Histologie and ultrastructural analyses demonstrated that these effects are not innocuous. While muscle fibers ultimately demonstrated hypertrophy and regeneration following a period of atrophy, distraction produced far more serious degenerative nerve and arterial changes.