DELAYED RESOLUTION OF NEPHROTIC SYNDROME FOLLOWING STEM CELL TRANSPLANT FOR AMYLOIDOSIS (AL)

摘要

In most malignancies, response following stem cell transplantation is assessed by the maximal reduction in tumor mass. In multiple myeloma, response is assessed using the surrogate of 50% reduction in M protein level (1). In AL, the goal of high-dose chemotherapy is eradication of the amyloidogenic protein production. The final endpoint is improvement in organ function for those organs involved with amyloid deposits.