Base Selection Method for Recognition of Exon-Intron Boundaries

摘要

The genes of eukaryotes like human beings are consisted of regulatory regions that controls transcription and structural regions which is consisted of exons where protains are coded and introns that are between exons. Since protains are generated from exons via transcription and splicing, recognition of exons plays an important role in revealing the functions of genes. Although the DNA sequence is known to be finite, a huge amount of array data are being produced day by day. In this situation, exons have to be extracted automatically and efficiently by computers. Lots of pieces of research work have been devoted for this purpose, and as a result systems like GENSCAN are widely used. This paper presents the base selection method that we developed for quick recognition of the exon-intron boundaries.