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Blood Levels of Organochlorine Pesticide Residues and Risk of Reproductive Tract Cancer Among Women from Jaipur, India

机译:英国斋浦尔妇女血液中有机氯农药残留的血液水平及妇女生殖道癌症

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Residues of organochlorine pesticides are integral part of our environment. Because of their strong lipophilic and non-biodegradable nature, organisms at higher trophic levels in the food chain tend to accumulate them. The aim of the present study was to assess the influence of organochlorine pesticides upon the occurrence of reproductive tract cancers in women from Jaipur, India. Blood samples were collected from 150 females. In that group, 100 females suffered from reproductive tract cancers like cervical, uterine, vaginal and ovarian cancers, while the rest did not suffer from cancers or any other major disease and were treated as control group. The collected blood samples were subjected to pesticide extraction and analyzed with the help of gas chromatography. The pesticides detected were benzene hexa chlororide and its isomers, dieldrin, heptachlor, dichloro diphenyl trichloro ethane and its metabolites. The data obtained indicate that the organochlorine pesticide residue levels were significantly higher in all the cancer patients as compared with the control group.
机译:有机氯杀虫剂的残留物是我们环境的组成部分。由于它们具有强烈的亲脂性和不可生物降解的性质,食物链中较高营养水平的生物倾向于积累它们。本研究的目的是评估有机氯农药对印度斋浦尔妇女生殖道癌的发生影响。从150名女性收集血样。在该组中,100名女性患有宫颈癌,子宫,阴道和卵巢癌等生殖道癌,而其余的未患有癌症或任何其他主要疾病,并被视为对照组。将收集的血液样品进行农药萃取,并在气相色谱的帮助下进行分析。检测到的杀虫剂是苯六到氯呢和其异构体,狄雷林,七氯,二氯二苯基三氯乙烷及其代谢物。所获得的数据表明,与对照组相比,所有癌症患者中有机氯农药残留水平明显高。

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