Periparturient ketosis is highly prevalent in the dairy industry and has been associated with a number of health problems, especially displaced abomasum and fatty liver infiltration, as well as decreased productivity and decreased fertility. Despite the importance of ketosis, thorough descriptive studies of naturally occurring periparturient ketosis are lacking. The objective of this observational study was to provide a detailed description of the spontaneous development of ketonemia in Holstein dairy cows in their first two weeks of lactation and to describe the associations between serum beta-hydroxybutyrate (BHBA) levels and other metabolites and milk production.
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