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Biophysical Character of Non-Viral Vector with Active Targeting Profile for Phosphatidylserine

机译:非病毒载体的生物物理特征,具有磷脂酰丝氨酸的活性靶向曲线

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A non-viral vector for the delivery of gene with active targeting profile for phosphatidylserine (PS) has been developed. This vector, M76001, shows high affinity for PS, and its circular dichroism spectra has revealed that structural change of M76001 in the presence of PS was related to its selective transfection to the PS-presenting cells such as activated immune response cells and cancer cells.
机译:已经开发出具有用于磷脂酰丝氨酸(PS)的活性靶向曲线的基因递送的非病毒载体。该载体M76001显示了对PS的高亲和力,其圆形二色谱揭示了PS存在下M76001的结构变化与其对PS呈递细胞的选择性转染如活性的免疫应答细胞和癌细胞有关。

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