Assessment of Mean Arterial Blood Pressure Using Spectral and Chaotic Analyses in Different Antihypertensive Drug Treatments

摘要

Mean arterial blood pressure (MABP) was analyzed by spectral and chaotic analyses in hypertensive patients. Two antihypertensive drugs, Cozaar and Renitec, were adopted to investigate the effects on MABP. 17 subjects were separated randomly into two groups, MABP was acquired during both supine and tilt-up positions before and after treatment. Correlation dimension (CD) was applied to evaluate the complexity of MABP, In spectral analysis, the ratio of low- to high-frequency power was increased more in the group with Renitec, It may indicate that Cozaar has more manifest effect for suppressing the activity of sympathetic nervous system. In the two groups, CD values of MABP increased in the supine position. The nonlinear analysis results might reveal that patients will tend to be normal with the two drugs.