Hyperthermia cancer therapy attempts to heat the tumor and maintain normal temperature in healthy tissue. This goal can be achieved through a waveform diversity method that optimizes the covariance matrix of the excitation signals applied to array elements. This paper presents the computer simulation of a cylindrical section ultrasound phased array using the waveform diversity method to heat a spherical tumor embedded in a 3D biological tissue model. With a simple optimization strategy, the optimal excitation sequences are obtained and a desirable power deposition and temperature distribution are achieved.
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