TWO-DIMENSIONAL ELECTROPHORESIS OF PROTEINS FROM HUMAN INTESTINAL CACO-2 CELLS EXPOSED TO THE KNOWN XENOESTROGEN NONYLPHENOL: Preliminary results

摘要

As plastics continue to replace traditional building materials worldwide, the production of alkylphenolic compounds, esp. nonylphenol, is expected to increase at a steady pace (Lorenc et al., 1992). Nonylphenol is used to harden PVC plastic and is also a stabilizer of polystyrene containers that are used to hold beverages such as milk and juices. This compound is also a degradation product of detergents and household cleaners, and as such, is found in wastewater effluents. Human exposure to alkylphenols, esp. nonylphenol from drinking water, is around 0.7 μg day~(-1) (Weeks et al., 1996).