Three dimensional woven bone tissue engineering scaffolds of melt-spun poly(lactic acid) fibers

摘要

The loss of bone mass increases and the bone quality deteriorates over the lifespan. As people live longer and expect to feel better, bone damage and fractures are even more serious health problems today than in the past and the need for human "spare parts" thus increases. The need for implants today is far greater than can be met by human donors. Since ethical concerns are raised, the ability to take advantage of organs from animals has been limited. Therefore, demand and knowledge of new technologies for tissue replacement are very high. In recent years, advances in cell biology and production of polymeric materials have opened up opportunities for a new surgery. Polymers are at the focus of the new technology known as tissue engineering.