Application of Noncontact Mapping System in Endocardial Mapping in the Porcine Model of Healed Myocardial Infarction

摘要

Detailed endocardial maps and linear ablation were done in six ventricular chambers of 4 pig 10 - 16 weeks after left anterior descending coronary artery infarction by noncontact mapping system during sinus rhythm. Mean infarction size determined by the system were 8.6+-2.7cm2 which had no difference from the size by pathology measurement. The location and the border of infarction were correlation to pathological analysis. Compared with remote sites, electrograms from infarction sites had smaller amplitudes, longer durations, and more frequent notched or late components. Border zone electrograms were intermediate in amplitude and duration. This noncontact mapping system allows accurate 3D characterization of infarction architecture and defines the relationship of electrophysiological and anatomic abnormalities. This technique may prove useful in devising anatomically based strategies for ablation of scar-related ventricular tachycardia.