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IBD-based QTL detection In cereal breeding programs

机译:基于IBD的QTL检测谷物育种计划

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Mapping quantitative trait loci in crop plants is usually based on bi-parental populations. Although high detection power can be achieved with such designs, the inferences that can be made are limited to the two parental lines, often leading to hardlyexploitable results. Besides, the cost of specific trials to perform QTL mapping is often a limitation for routinely map QTL. On the other hand, conventional breeding programs use a lot of crosses with many different parents. The resulting selfed progeny represents a real picture of the improved material, on which many quantitative trait notations are available because of their use during the selection process. The development of statistical techniques able to map QTL in any kind of inbred populations,like breeding populations, is challenging, mainly to be widely used by-breeders in conventional breeding programs. We present here a two step variance component technique based on the calculation of the Identity-By-Descent probabilities to routinely mapQTL in any kind of inbred pedigree. The performance of the QTL mapping methodology is assessed using simulated data which mimic an real recurrent pedigree selection. The capacity of the technique to accurately estimate parameters is investigated for a wide range of scenarios.
机译:作物植物中的定量性状基因座通常基于双父群。尽管通过这种设计可以实现高检测功率,但是可以制造的推断仅限于两个父母线,通常导致硬化的结果。此外,执行QTL映射的特定试验的成本通常是常规地图QTL的限制。另一方面,传统的育种计划使用许多不同父母的大量交叉。得到的自私后代代表了改进材料的真实图,因为它们在选择过程中使用而获得许多定量特性符号。能够在任何类型的血统群体中映射QTL的统计技术的发展,如繁殖人口,是挑战性的,主要是在传统育种计划中被广泛使用的育种者广泛使用。我们在这里介绍了两个步骤方差分量技术,基于计算逐个逐个概率来常规地MAPQTL以任何类型的读数谱系。使用模拟数据来评估QTL映射方法的性能,这些数据模仿真正的复发性谱系选择。对精确估计参数的技术的能力进行了广泛的情景。

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