Evaluation of a siderophore receptor and porin vaccine composition derived from Salmonella Newport and Escbericbia coli in swine

摘要

Pathogenic bacteria require iron for growth and survival. But iron is also essential to animal hosts, which lock away iron using high-affinity soluble proteins such as heme and transferrin. Therefore, in order for bacteria to successfully invade and infect a host, they must utilize their own special iron-gathering protein systems to compete with the host for iron.