KIDNEY SITE-SELECTIVE DELIVERY OF 5-FLUOROURACIL UTILIZING THE ABSORPTION ON THE KIDNEY SURFACE IN RATS

机译：肾脏位点 - 选择性递送5-氟尿嘧啶，利用大鼠肾脏表面的吸收

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The present study was undertaken to elucidate the organ- and/or site-selective delivery of 5-fluorouracil (5-FU) to the kidney following the application to the kidney surface in rats. This novel organ- and/or site-selective drug delivery system is expected to be safe and effective treatment for the renal cell carcinoma, which localized in the part of kidney.

机译：本研究旨在在大鼠肾脏表面施加到肾脏表面之后阐明5-氟尿嘧啶（5-FU）的器官和/或部位选择性递送5-氟脲（5-FU）。该新型器官和/或场地选择性药物输送系统预计将安全有效地治疗肾细胞癌，该肾细胞癌局部局部地局部化。

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《Annual meeting of the Controlled Release Society》|2002年||共2页
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S. Kawakami; T. Horimoto; T. Mukai; K. Nishida; M. Nakashima; H. Sasaki; T. Sakaeda; J. Nakamura;
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中图分类制药化学工业;
关键词
site-specific delivery; targeted delivery; tumor drug delivery;

机译：特定网站递送;有针对性的交付;肿瘤药物递送;

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专利

1. Kidney- and site-selective delivery of 5-fluorouracil utilizing the absorption on the kidney surface in rats. [J] . Kawakami S, Horimoto T, Nishida K, Biological & pharmaceutical bulletin . 2002,第7期

机译：利用大鼠肾脏表面的吸收，通过5-氟尿嘧啶对肾脏和部位进行选择性转运。
2. Further Studies on the Kidney-and Site-Selective Delivery of 5-Fluorouracil Following Kidney Surface Application in Rats [J] . Junzo Nakamura, Tomomi Horimoto, Ryu Hirayama, Biological & pharmaceutical bulletin . 2003,第12期

机译：大鼠肾脏表面应用后5-氟尿嘧啶的肾脏和位点选择性递送的进一步研究
3. Effect of the absorption enhancer saponin on the intrarenal distribution of 5-fluorouracil following its kidney surface application in rats. [J] . Nakamura J, Horimoto T, Hirayama R, Biological & pharmaceutical bulletin . 2003,第7期

机译：大鼠体内肾脏表面吸收增强剂皂苷对5-氟尿嘧啶肾内分布的影响。
4. KIDNEY SITE-SELECTIVE DELIVERY OF 5-FLUOROURACIL UTILIZING THE ABSORPTION ON THE KIDNEY SURFACE IN RATS [C] . S. Kawakami, T. Horimoto, T. Mukai, Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：肾脏对肾脏表面吸附的5-氟尿嘧啶肾脏选择性转运
5. Saving lives through increasing available donor kidneys: The positive effect of altruistic kidney paired donor chains. [D] . Harmon, Nikita Denise. 2013

机译：通过增加可用的供体肾脏来挽救生命：利他的肾脏配对供体链的积极作用。
6. Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: Pharmacokinetics of γ-hydroxybutyric acid and L-lactate in rats [O] . Rutwij A. Dave, Marilyn E. Morris -1

机译：结合生理相关的液体重吸收和转运蛋白介导的肾脏重吸收的半机械肾脏模型：γ-羟基丁酸和L-乳酸在大鼠中的药代动力学
7. Kidney- and Site-Selective Delivery of 5-Fluorouracil Utilizing the Absorption on the Kidney Surface in Rats [O] . Kawakami, Shigeru, Horimoto, Tomomi, Nishida, Koyo, 2002

机译：利用大鼠肾脏表面吸收的5-氟尿嘧啶肾脏和位点选择性递送

KIDNEY SITE-SELECTIVE DELIVERY OF 5-FLUOROURACIL UTILIZING THE ABSORPTION ON THE KIDNEY SURFACE IN RATS

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