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Improvement of Electrical Properties of Si-Microprobe Electrode Arrays for Neural Recording

机译:用于神经记录的Si-Microprobe电极阵列电性能的改进

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This paper reports on realization of Si-microprobe array and improvement of electrical properties of the probe array as multi-electrode neural recording sensor. Si microprobe can be formed on Si(111) substrate by Vapor-Liquid-Solid (VLS) crystal growth using Au as catalyst and Si{sub}2H{sub}6 as gas source of Si. VLS method uses low temperature of about 600°C and hence it is compatible with IC process, such as making amplifiers or impedance converters. Thus, Si microprobe can become very useful sensing device to measure neural signals which has very small voltage change of tens μV order. Si microprobe is also minimally-invasive for penetrating tissue because the probe has very small diameter and narrow tip. The tip of Si probe should be covered biocompatible metal film to keep living and make it a snap to measure electrical signal in tissue fluid. So the metal film dictates electrical property of the Si probe as biomedical electrode. In bioinstrumentation field, Au is commonly used as metal electrode; however, it is known that Pt or Ir can be finer than Au as biomedical electrode. Therefore, we report applying Pt and Ir to Si probe.
机译:本文关于实现Si-Microprobe阵列和探针阵列的电特性的提高报告为多电极神经记录传感器。通过使用Au作为催化剂和Si {Sub} 2H {Sub} 6作为Si的气源,可以在Si(111)晶体上通过蒸汽 - 液固 - 固体(VLS)晶体生长在Si(111)底板上形成。 VLS方法使用约600°C的低温,因此它与IC工艺兼容,例如制造放大器或阻抗转换器。因此,Si微探测器可以变得非常有用的感测装置,以测量具有非常小的电压变化的神经信号。对于穿透组织,Si微探测器也是微创的,因为探针具有非常小的直径和窄尖端。 Si探针的尖端应覆盖生物相容的金属膜以保持生活,并使其成为测量组织液中的电信号。因此,金属膜规定了Si探针作为生物医学电极的电性能。在生物仪最低的领域中,Au通常用作金属电极;然而,已知Pt或IR可以比au更精细,作为生物医学电极。因此,我们向SI探测器报告应用PT和IR。

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