FIRST REPORT OF POSTWEANING MULTISYSTEMIC WASTING SYNDROME IN MEXICO

摘要

Postweaning multisystemic wasting syndrome (PMWS) is an emergent disease associated with porcine circovirus type 2 (PCV2) infection. This syndrome is clinically characterized by loss of body weight, paleness of the skin and, occasionally, icterus. Respiratory distress and diarrhoea may occur in a variable degree in PMWS cases. Macroscopic lesions include generalized lymph nodes enlargement and tan-mottled lungs. Histopathological lesions in lymphoid tissues are almost unique for this disease, and include lymphocyte depletion, granulomatous inflammation and, sometimes, grape-like, intracitoplasmic inclusion bodies of PCV2. Definitive PMWS diagnosis is established based on compatible clinical signs, histopathologic lesions in lymphoid tissues, and PCV2 detection within the lesions. PMWS has been described worldwide, and also in North American countries such as Canada and United States; the presence of this disease in Mexico, although suspected, was unknown. Then, the objective of the present work was to study the presence of PCV2 infection and PMWS in Mexico.