CHEMEQ~(RTM) polymeric antimicrobial, active ingredient: (poly [2-propenal, 2-propenoic acid]), is an aldehyde antimicrobial polymer that has a different mode of action to current antibiotics. Earlier experimental infection studies and field trials with CHEMEQ~(RTM) polymeric antimicrobial showed that it had therapeutic value in the control of PWC. The post-weaning period in pigs is accompanied by environmental and nutritional changes, and withdrawal of passive immunity: consequently it represents the time of greatest morbidity and mortality. Changes in mucosal surfaces of the gut and intestinal microbiota can negatively affect the establishment of a healthy gut immune system, and reduce disease resistance in the weaned pig. Proliferation of enterotoxigenic strains of Escherichia coli at this time can result in severe secretory diarrhoea: postweaning colibacillosis (PWC). The withdrawal of antibiotic growth promoters will profoundly influence the endemic nature of PWC in piggeries throughout the world. This was highlighted in Denmark where the withdrawal of antibiotic growth promoters for weaner pigs resulting in increases in morbidity and mortality, and decreases in average daily gain as a result of PWC. This trial was undertaken to further evaluate the product under field conditions.
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