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Distribution of childhood thyroid dose among cohort members for epidemiological health study in the Bryansk region

机译:BRYANSK地区流行病学卫生研究中儿童甲状腺剂量的分布

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With the aim of carrying out a long-term medical follow-up with radiation dose reconstruction, a cohort of subjects was selected among inhabitants of the most contaminated area in Russia following the Chernobyl accident (the western districts of Bryansk region). The cohort is comprised of 1065 subjects who were under 10 years old at the time of the accident, Most of them were examined on health status in the Chernobyl Sasakawa Health and Medical Cooperation Project, Since the main findings of studies in the project were thyroid abnormalities, selection of subjects was conducted on the basis of the plausible estimates of radiation dose to the thyroid, To estimate thyroid doses, the data from direct measurements of ~(131)I in the thyroid and questionnaire data on individual dietary habits in May 1986 were used. Reasonable approximations were applied to reconstruct individual doses from available data, including doses for those persons who had not been measured for thyroidal radioiodine. The distribution ofinternal radiation dose to the thyroid among cohort members was obtained. The individual doses to particular subjects are estimated with inevitably essential degree of uncertainty, However, the distribution of subjects into wide dose intervals, from under 200 mGy to over 2 Gy, seems to be an acceptable approach for cohort study in radiation epidemiology.
机译:目的是在切尔诺贝利事故(Bryansk地区的西部地区)之后,在俄罗斯最污染的地区的居民中选择了一种长期医学随访的长期医学随访。队列由1065名受试者组成,在事故发生时1065名受试者,其中大多数都在切尔诺克川卫生和医疗合作项目中审查了卫生地位,因为该项目研究的主要结果是甲状腺异常,在辐射剂量对甲状腺的合理估计的基础上进行受试者的选择,以估计甲状腺剂量,从1986年5月在甲状腺直接测量中的数据〜(131)中的数据和调查问卷数据用过的。应用合理的近似以从可用数据重建个体剂量,包括那些未测量甲状腺放射性碘的人的剂量。获得了群组成员中甲状腺间隔辐射剂量的分布。特定对象的个体剂量估计是不可避免的必要性的不确定性,然而,受试者分布在宽剂量间隔,从200岁到2岁以下的时间间隔,似乎是辐射流行病学中的队列研究的可接受方法。

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