Hormone levels associated with immune responses among inhabitants in HLNRAs of Ramsar-Iran

摘要

The purpose of this study was to determine whether the exposure to HLNR affects the hormone levels associated with immune responses in young and elderly subjects. The studies demonstrated a decreased level of DHEA and increased level of cortisol in the elderly HLNRA group which might be possibly associated with higher cumulative doses. There was a higher incidence of hypothyroidism in the HLNRA group, mostly in elder group. A significant increase of CD69 expression on CD4+ T lymphocytes was found in the young HLNRA group. Low levels of DHEA in the elder group were correlated to their increased IgE levels.